Tag: 爱上海HA

first_imgTickets are now on sale for the innovative new staging of Oklahoma! from director Daniel Fish, set to arrive at Broadway’s Circle in the Square Theatre. Previews will begin on March 19 with an opening night of April 7 for a limited run through September 1.The interior of the Circle in the Square will be repurposed as a community hall for the production, which coincides with the iconic Rodgers & Hammerstein musical’s 75th anniversary. The intimate staging features a seven-piece band and chili served to the audience at intermission.The production was originally developed and presented at the Fisher Center for the Performing Arts at Bard College in 2015. A more recent production played Brooklyn’s St. Ann’s Warehouse in 2018. Related Shows Oklahoma! View Comments Show Closed This production ended its run on Jan. 19, 2020last_img read more

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first_imgFDA urges hospitals to start using duodenoscopes with disposable partsThe US Food and Drug Administration (FDA) says it will now recommend that hospitals move away from using duodenoscopes with reusable parts because of concerns about patient infections that have been linked to cleaning issues.In a safety communication issued yesterday, the FDA said it’s recommending that hospitals and endoscopy facilities transition away from fixed endcap duodenoscopes, which are used to diagnose and treat conditions of the pancreas and bile ducts, to those with newer design features that “facilitate or eliminate the need for reprocessing.” The agency says it’s working with manufacturers to increase the supply of disposable cap duodenoscopes and encourage development of innovative device designs that reduce the risk of infection, and that it recognizes a full transition away from conventional duodenoscopes will take time.Fixed endcap duodenoscopes have been linked to a number of outbreaks of multidrug-resistant bacteria at US and European hospitals in recent years, including a January 2015 carbapenem-resistant Enterobacteriaceae outbreak that resulted in two deaths at a Los Angeles hospital. Because of the complex design of the devices, they can be difficult to clean and have been found to harbor dangerous bacteria that can be transmitted to other patients, even after being properly cleaned. The FDA issued a safety warning in 2015 and device manufacturers updated their cleaning instructions, but problems have persisted.Duodenoscopes are used in more than 500,000 endoscopic retrograde cholangiopancreatography procedures each year in the United States.The FDA said that, during the transition period, hospitals and endoscopy facilities should ensure that staff members are meticulously following duodenoscope reprocessing instructions, institute quality control programs that include sampling and microbiologic culturing, and develop schedules for routine inspection. The agency also noted that patients should be aware that the risk of infection from inadequate cleaning is relatively low, and that they should discuss the risks and benefits with their providers before cancelling or delaying planned procedures.Aug 29 FDA safety communication Oral omadacycline found non-inferior to linezolid for skin infectionsDrug maker Paratek Pharmaceuticals reported yesterday in The Lancet Infectious Diseases that and oral version of omadacycline—its FDA-approved antibiotic for community-acquired and pneumonia and skin infections—was found to be non-inferior to oral linezolid in adults with acute bacterial skin and skin-structure infection (ABSSSI).In the phase 3 OASIS 2 trial, which was funded by Paratek, eligible adults with ABSSSI at 33 US hospitals were randomly assigned to receive one dose of oral omadacycline or two doses of linezolid for 7 to 14 days. The primary end points were early clinical response (48 to 72 hours after the first dose) in the modified intention-to-treat (mITT) population, and investigator-assessed clinical response at post-treatment evaluation in the mITT population and clinically evaluable population. The non-inferiority margin was 10%.Overall, 735 participants were randomly assigned, with 368 receiving omadacycline and 367 receiving linezolid. The results showed that omadacycline (315 of 360, 88%) was non-inferior to linezolid (297 of 360, 83%) for early clinical response in the mITT population (percentage-point difference 5.0; 95% confidence interval [CI], −0.2 to 10.3). For investigator-assessed clinical response at post-treatment evaluation, omadacycline (303 of 360, 84%) was non-inferior to linezolid (291 of 360 81%) in the mITT population (percentage-point difference 3.3; 95% CI, −2.2 to 9.0) and in the clinically evaluable population (278 of 284 [98%] vs 279 of 292 [96%]; percentage-point difference, 2.3; 95% CI, −0.5 to 5.8).The safety analysis showed that at least one treatment-emergent adverse event occurred in 197 of 368 omadacycline patients (54%), compared with 137 of 367 linezolid patients (37%), and that mild-to-moderate nausea and vomiting were more frequent in omadacycline patients (111 of 368 [30%] and 62 of 368 [17%], respectively) than in linezolid patients (28 of 367 [8%] and 11 of 367 [3%], respectively).The authors of the study write, “Considering the substantial burdens associated with initial inpatient management of skin infections, oral omadacycline is a new once-daily option to treat ABSSSI that might be considered as an alternative to linezolid.”Aug 29 Lancet Infect Dis study Data show vancomycin-resistant Enterococcus faecium rising in GermanyData from the German Antimicrobial Resistance Surveillance System show a 43% increase in vancomycin-resistant Enterococcus faecium (VREF) in German hospitals, according to a new study in Antimicrobial Resistance and Infection Control.For the study, researchers from Germany’s Robert Koch Institute analyzed data from routine vancomycin susceptibility testing of 35,906 clinical E faecium isolates collected from 148 hospitals from 2012 through 2017. The analysis found that the proportions of E faecium isolates exhibiting resistance to vancomycin increased from 11.2% in 2014 to 26.2% in 2017. The rise in VREF proportions was primarily seen in southern Germany, increasing from 10.8% in southwest Germany and 3.8% in southeastern Germany in 2014 to 36.7% and 36.8% in 2017, respectively.Further analysis found that VREF proportions were considerably higher in isolates from patients aged 40 to 59 years compared with younger patients, and that E faecium samples collected in specialist care hospitals and prevention and rehabilitation care hospitals were more likely to be vancomycin resistant than those from secondary care hospitals (odds ratios: 2.4 [95% CI, 1.2 to 4.6] and 2.4 [95% CI, 1.9 to 3.0], respectively).The authors of the study note that similar VREF increases have been found in countries neighboring Germany, including Denmark, Belgium, Poland, and the Czech Republic.They conclude, “Continued surveillance and implementation of effective infection prevention and control measures accounting for local resistance differences are needed to reduce the spread of vancomycin-resistant E. faecium in German hospitals.”Aug 28 Antimicrob Resist Infect Control studylast_img read more

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first_imgAmpliTech Group announced that they received over $1 million worth of orders in the 4th Quarter of 2015. The company also announced that they reached a record high in revenues for 2015 which amounts to a 16% increase over last year’s revenue.AmpliTech’s strategy for increasing revenue and profitability is working and with the large increase in bookings this year, they expect to have a great future as well. With new products coming out next year and continued sales and marketing strategy, the company expects revenue will continue to increase. Also, with new lower rate financing, they hope to improve their throughput as well as their bottom line.AmpliTech also announced that they will be moving into a new larger facility with double the space. This will improve production and increase the overall efficiency of their manufacturing and development process. The company plans to move into the new facility by February 1st, 2016.last_img read more

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first_imgDia mengatakan, baik orang tua ataupun pengasuh bisa membantu mengajarkan anak-anak bagaimana agar tetap berada di sebelah kiri saat berjalan, melihat kondisi lalu lintas di sekitar mereka berjalan, menggunakan jalur yag benar. Selain itu juga diajarkan bagaimana cara melewati atau mendahului pengguna jalan lain dengan aman, menggunakan sinyal tangan dan cara sopan bersepeda dengan kelompok mereka.Jika mengendarai sepeda, bermain scoot dan skating, helm merupakan alat keselamatan paling utama dan harus digunakan untuk melindungi kepala dari cedera. Helm yang digunakan juga harus ada stiker khusus yang di setujui standar helm.Sebelum mengantar anak mereka berangkat ke sekolah sampai ke jalanan, berlututlah untuk menjadi setinggi mereka. Sebab dengan cara ini, orang tua bisa melihat sudut pandang anak-anak di jalanan dan menjelaskan potensi bahaya yang akan terjadi dan memberikan informasi untuk penanganannya.Akurangi mengatakan, begitu pula bila orang tua mengantar anak mereka dengan mobil, pastikan mobil berhenti dengan tepat dan biarkan anak-anak masuk atau keluar dari mobil di sisi jalan setapak bukan jalan raya.“Jika pergi dengan bus, anak-anak harus mengerti untuk berdiri di tempat perhentian bus saat menunggu. Naik dan turunlah saat bus benar-benar berhenti untuk menghindari cedera karena terburu-buru,” ujar Akurangi.Dengan adanya peringatan di atas, pihak kepolisian juga ingin agar orang tua kembali menguji cara menjaga keselamatan anak-anak sebelum sekolah dimulai kembali. Manajer operasi pemolisian jalan Inspektur Peter McKennie mengatakan bahwa liburan musim panas yang lama membuat sebagian anak mungkin telah melupakan beberapa peraturan dasar yang harus mereka ikuti agar aman di perjalanan.“Menambah kegembiraan mereka untuk kembali ke sekolah dan melihat teman mereka dan ini bisa berarti mereka akan kurang waspada terhadap bahaya lalu lintas di sekitar mereka,” ujar McKennie. Pihak kepolisian meminta orang tua untuk duduk bersama anak mereka sebelum akhir liburan dan berdiskusi tentang peraturan keselamatan jalan, terutama anak-anak yang akan pergi ke sekolah sendiri.Baca juga: Perkenalkan Flagman, Robot Pengatur Lalu Lintas di India“Bantu mereka untuk memilih rute teraman untuk sampai ke sana dan melakukan beberapa latihan berjalan atau bersepeda bersama mereka, jadi mereka terbiasa dengan rute dan tempat teraman untuk menyeberang. Uji pengetahuan keselamatan jalan anak-anak Anda sebelum sekolah dimulai kembali. Saat anak-anak kembali ke sekolah minggu depan, kami ingin orang tua meluangkan waktu untuk memeriksanya agar sesuai dengan keamanan jalan,” ujarnyaShare this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… RelatedAtasi Kebosanan Selama Penerbangan, Emirates Rancang Program Khusus Untuk Anak28/10/2017In “Destinasi”Tingkatkan Keamanan Bus Sekolah, IMMI Kembangkan Fitur SafeGuards FlexPlus21/03/2018In “Bus dalam kota”Hadapi Karantina Wilayah, Ini 8 Hal yang Bisa Anda Lakukan Bersama Anak di Rumah31/03/2020In “Featured” Ilustrasi orang tua saat mengajarkan anak tentang keselamatan di jalan raya (gisborneherald.co.nz) Lalu lintas jalan raya yang padat bisa saja membuat orang melupakan keselamatan dirinya bahkan orang lain. Padahal kehati-hatian adalah kunci dalam keselamatan baik saat berkendara maupun berjalan kaki. Di Grisborne, Oakland, Amerika Serikat, anak-anak diajak untuk kembali belajar tentang keselamatan diri mereka di jalan raya baik saat pergi maupun pulang dari sekolah.Baca juga: Serba-Serbi Rumble Strip, “Polisi Tidur Mini” Yang Kerap Dijumpai di Jalan TolPetugas pendidikan keselamatan di jalan, Tairawhiti Dianne Akurangi mengatakan ingin memastikan anak-anak dan orang tua tetap aman dalam perjalanan mereka ke dan dari sekolah dengan transportasi apapun. “Anak-anak dibawah 10 tahun harus selalu bersepeda dengan orang dewasa,” ujar Akurangi yang dikutip KabarPenumpang.com dari laman gisborneherald.co.nz (26/1/2018).last_img read more

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